Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718145 | 0.95 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1GAAKMT2ACES2 | |
| SCHEMBL3718147 | 0.86 | FBP1 (0.38) | L3MBTL1ALDH1A1GAATSHRTDP1 | |
| SCHEMBL5737042 | 0.85 | KMT2A (0.48) | L3MBTL1ALDH1A1KMT2ATSHRTDP1 | |
| SCHEMBL27675955 | 0.82 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1GAATSHRTDP1 | |
| SCHEMBL13150211 | 0.80 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1GAAKMT2AMAPT | |
| SCHEMBL5736978 | 0.79 | KMT2A (0.50) | L3MBTL1ALDH1A1GAAKMT2ATSHR | |
| SCHEMBL3131921 | 0.79 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1GAAKMT2ACES2 | |
| SCHEMBL5696593 | 0.77 | MAPT (0.43) | ALDH1A1GAAKMT2ACES2ACHE | |
| SCHEMBL18698095 | 0.77 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1GAAKMT2ATSHR | |
| SCHEMBL1715464 | 0.76 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1GAATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116270-A1 | EP2/4 AGONISTS | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| WO-2009106534-A1 | NOVEL HETEROCYCLIC CARBOXAMIDES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |