Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CCNT2 | O60583 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721978 | 0.87 | CCNE1 (0.42) | CDK2CCNE1CCNE2CCNT1CCNT2 | |
| SCHEMBL3718466 | 0.86 | CCNE1 (0.43) | CDK2CCNE1CCNE2CCNT1CCNT2 | |
| SCHEMBL3718371 | 0.85 | CDK2 (0.54) | CDK2CCNE1CCNE2CCNT1CCNT2 | |
| SCHEMBL3724809 | 0.83 | CDK2 (0.40) | CDK2CCNE1CCNE2KMT2ACCNA2 | |
| SCHEMBL3719455 | 0.83 | CDK2 (0.52) | CDK2CCNE1CCNE2CCNT1CDK9 | |
| SCHEMBL3716187 | 0.83 | CDK2 (0.43) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3718696 | 0.82 | CDK2 (0.43) | CDK2CCNE1CCNE2CCNT1CCNT2 | |
| SCHEMBL3718665 | 0.82 | CDK1 (0.44) | CDK2CCNE1CCNE2ALDH1A1MEN1 | |
| SCHEMBL3719064 | 0.82 | CYP3A4 (0.43) | CDK2CCNE1CCNE2HTTCCNA2 | |
| SCHEMBL3719473 | 0.82 | CDK2 (0.65) | CDK2CCNE1CCNE2CCNT1CCNT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139288-A1 | 5,7-DISUBSTITUTED 3-ISOPROPYLPYRAZOLO[4,3-D]PYRIMIDINES FOR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS | C3 BIO GMBH (DE) | 2010-12-09 | — | — | WO | disclosed |