Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | TEC | P42680 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718570 | 0.93 | TSHR (0.38) | TSHRCYP1A2CYP3A4NFKB1KDM4E | |
| SCHEMBL3720128 | 0.89 | KDM4E (0.45) | TSHRCYP1A2CYP3A4NFKB1KDM4E | |
| SCHEMBL3720741 | 0.88 | FFAR4 (0.36) | TSHRCYP1A2CYP3A4NFKB1KDM4E | |
| SCHEMBL3720774 | 0.87 | GLA (0.43) | TSHRCYP1A2CYP3A4NFKB1KDM4E | |
| SCHEMBL3719835 | 0.86 | FFAR4 (0.36) | TSHRCYP1A2CYP3A4NFKB1KDM4E | |
| SCHEMBL3717501 | 0.86 | GLA (0.39) | TSHRCYP1A2CYP3A4NFKB1KDM4E | |
| SCHEMBL3717202 | 0.85 | ACACB (0.38) | TSHRCYP1A2CYP3A4NFKB1LMNA | |
| SCHEMBL3719552 | 0.85 | PDE3B (0.34) | LMNAMEN1KMT2AS1PR3S1PR5 | |
| SCHEMBL3719380 | 0.85 | RXRA (0.37) | TSHRCYP1A2CYP3A4NFKB1S1PR3 | |
| SCHEMBL3722047 | 0.84 | GLA (0.42) | TSHRCYP1A2CYP3A4NFKB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |