Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 9/20 | 0.34 |
| ▸ | ACACA | Q13085 | 7/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716838 | 0.93 | ACACB (0.33) | ACACBACACAHDAC1HDAC2S1PR3 | |
| SCHEMBL3717771 | 0.89 | MEN1 (0.37) | PDE3BPDE3AACACBACACAHDAC1 | |
| SCHEMBL3724495 | 0.88 | PDE3B (0.34) | PDE3BPDE3AACACBACACAPOLB | |
| SCHEMBL3720459 | 0.87 | ACACB (0.38) | PDE3BPDE3AACACBACACA | |
| SCHEMBL3721410 | 0.86 | MAPT (0.36) | PDE3BPDE3AMAPK1MEN1NPC1 | |
| SCHEMBL3726328 | 0.85 | ACACB (0.40) | PDE3BPDE3AACACBACACAPOLB | |
| SCHEMBL3718486 | 0.85 | TSHR (0.37) | ACACBACACAS1PR3S1PR5FFAR4 | |
| SCHEMBL3720016 | 0.85 | RXRA (0.39) | S1PR3S1PR5FFAR4 | |
| SCHEMBL3726780 | 0.84 | PPARG (0.36) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3716745 | 0.83 | XDH (0.35) | ACACBHDAC1HDAC2XDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |