Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356346 | 0.89 | ENPP2 (0.51) | LTA4HENPP2LAP3RENMAOB | |
| SCHEMBL4345257 | 0.89 | ENPP2 (0.51) | LTA4HENPP2LAP3RENMAOB | |
| SCHEMBL12783530 | 0.88 | ACACB (0.50) | LTA4HENPP2LAP3MAOBMME | |
| SCHEMBL5945448 | 0.87 | REN (0.54) | ENPP2REN | |
| SCHEMBL13630987 | 0.87 | REN (0.54) | ENPP2REN | |
| SCHEMBL24324236 | 0.86 | TRPM8 (0.56) | ACE2CTSKTRPM8CTSSSPPL2A | |
| SCHEMBL5413813 | 0.86 | TRPM8 (0.56) | ACE2CTSKTRPM8CTSSSPPL2A | |
| SCHEMBL7698179 | 0.86 | TRPM8 (0.56) | ACE2CTSKTRPM8CTSSSPPL2A | |
| SCHEMBL4910315 | 0.86 | TRPM8 (0.56) | ACE2CTSKTRPM8CTSSSPPL2A | |
| SCHEMBL15195992 | 0.86 | ENPP2 (0.55) | LTA4HENPP2RENMAOBMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135424-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-11-25 | — | — | WO | disclosed |