Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422780 | 0.97 | HPGD (0.45) | HPGDHSD11B1ALDH1A1KDM4EGRM5 | |
| SCHEMBL23387941 | 0.75 | HPGD (0.55) | HPGDHSD11B1ALDH1A1KDM4ETSHR | |
| SCHEMBL3717205 | 0.73 | HCAR2 (0.48) | ALDH1A1KDM4EPOLBTSHRMEN1 | |
| SCHEMBL1427046 | 0.72 | MEN1 (0.59) | HPGDHSD11B1ALDH1A1KDM4EGRM5 | |
| SCHEMBL3778711 | 0.72 | HPGD (0.58) | HPGDHSD11B1ALDH1A1KDM4ETSHR | |
| SCHEMBL4926896 | 0.72 | CA5A (0.35) | MEN1KMT2A | |
| SCHEMBL1035373 | 0.72 | NNMT (0.39) | POLBTSHR | |
| SCHEMBL20577446 | 0.70 | GRM5 (0.54) | HPGDHSD11B1ALDH1A1KDM4EGRM5 | |
| SCHEMBL743014 | 0.70 | HPGD (0.53) | HPGDALDH1A1KDM4EGRM5POLB | |
| SCHEMBL6824364 | 0.70 | GRM5 (0.51) | HPGDHSD11B1GRM5CNR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092342-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE AS THE MODULATORS OF THE TRPV1 RECEPTOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | WO | disclosed |