Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201946 | 0.87 | FDPS (0.41) | FDPSEPHX1CA1CA2CA12 | |
| SCHEMBL8833635 | 0.83 | FDPS (0.39) | FDPSEPHX1CA1CA2CA12 | |
| SCHEMBL18084197 | 0.82 | FDPS (0.38) | FDPSCA2CA12CA9 | |
| SCHEMBL28847191 | 0.75 | CA1 (0.42) | EPHX1CA1CA2CA12CA9 | |
| SCHEMBL27722580 | 0.73 | PGR (0.45) | FDPSEPHX1CA1CA2 | |
| SCHEMBL1432484 | 0.73 | PGR (0.45) | FDPSEPHX1CA1CA2 | |
| SCHEMBL354320 | 0.73 | APP (0.35) | FDPSEPHX1CA1CA2CA12 | |
| SCHEMBL1432353 | 0.72 | CA1 (0.34) | FDPSEPHX1CA1CA2CA12 | |
| Palmitic Acid SCHEMBL28958123 | 0.72 | GPR84 (0.55) | — | |
| Stearic Acid SCHEMBL28069035 | 0.72 | GPR84 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |