Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722465 | 0.92 | TRPV1 (0.43) | TRPV1ACACBMTNR1ASMN1; SMN2LTA4H | |
| SCHEMBL3802105 | 0.91 | TRPV1 (0.45) | TRPV1MTNR1ASMN1; SMN2LTA4HEPHX2 | |
| SCHEMBL3720261 | 0.88 | ACACB (0.51) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3720617 | 0.87 | ACACB (0.47) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3717663 | 0.84 | GLA (0.40) | SMN1; SMN2 | |
| SCHEMBL3721719 | 0.82 | PPARA (0.35) | SMN1; SMN2LMNA | |
| SCHEMBL3721086 | 0.82 | HTT (0.39) | TRPV1EPHX2SCN9AMAPTLMNA | |
| SCHEMBL3722415 | 0.80 | ACACB (0.51) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3719222 | 0.80 | ACACB (0.47) | ACACB | |
| SCHEMBL3720850 | 0.79 | PPARA (0.43) | TRPV1ACACBMTNR1ASMN1; SMN2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |