Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726761 | 0.87 | SMN1; SMN2 (0.35) | LMNAHTTSMN1; SMN2TDP1 | |
| SCHEMBL3726782 | 0.86 | HCRTR1 (0.35) | PPARAPPARDHCRTR1HCRTR2SCN3A | |
| SCHEMBL3717663 | 0.85 | GLA (0.40) | RORCHCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL3724221 | 0.85 | S1PR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL3719224 | 0.82 | TRPV1 (0.46) | LMNASMN1; SMN2 | |
| SCHEMBL3721086 | 0.81 | HTT (0.39) | PPARAPPARDLMNAHTTMRGPRX4 | |
| SCHEMBL3717662 | 0.79 | AKR1C3 (0.36) | RORCSCN3ALMNAHTTSMN1; SMN2 | |
| SCHEMBL3720060 | 0.77 | FFAR1 (0.34) | PPARAPPARDPPARGLMNAHTT | |
| SCHEMBL3726994 | 0.76 | ACACB (0.42) | SMN1; SMN2 | |
| SCHEMBL3719222 | 0.76 | ACACB (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |