Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719224 | 0.88 | TRPV1 (0.46) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3722415 | 0.87 | ACACB (0.51) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3726818 | 0.86 | ACACB (0.64) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3728669 | 0.84 | KDM4E (0.57) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3720307 | 0.83 | MTNR1A (0.61) | ACACBMTNR1ASMN1; SMN2MTNR1B | |
| SCHEMBL3722351 | 0.82 | SMN1; SMN2 (0.54) | MTNR1ASMN1; SMN2MTNR1BMAPTALDH1A1 | |
| SCHEMBL3720263 | 0.81 | LMNA (0.40) | ACACBMTNR1ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3724679 | 0.80 | ACACB (0.51) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3724593 | 0.80 | ACACB (0.59) | ACACBMTNR1ASMN1; SMN2MTNR1BMAPT | |
| SCHEMBL3802105 | 0.80 | TRPV1 (0.45) | MTNR1ASMN1; SMN2MTNR1BMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |