Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720421 | 0.87 | ACACB (0.41) | ESRRASCN9A | |
| SCHEMBL3726759 | 0.87 | CREBBP (0.43) | HTTLMNAESRRACREBBPALDH1A1 | |
| SCHEMBL3724217 | 0.85 | CREBBP (0.48) | HTTCREBBPALDH1A1MAPK1GAA | |
| SCHEMBL3719224 | 0.82 | TRPV1 (0.46) | LMNAALDH1A1EPHX2SCN9ATRPV1 | |
| SCHEMBL3719222 | 0.82 | ACACB (0.47) | — | |
| SCHEMBL3721719 | 0.81 | PPARA (0.35) | HTTLMNAMRGPRX4PPARAPPARD | |
| SCHEMBL3717663 | 0.79 | GLA (0.40) | MAOB | |
| SCHEMBL3717662 | 0.79 | AKR1C3 (0.36) | HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL3720059 | 0.77 | MAOB (0.43) | LMNACREBBPALDH1A1MAPK1MAOB | |
| SCHEMBL3726992 | 0.76 | ESRRA (0.53) | HTTESRRACREBBPALDH1A1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |