Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 1/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529415 | 1.00 | CAPN1 (0.62) | CAPN1PPARGPPARACTSBFFAR1 | |
| SCHEMBL12475011 | 0.87 | CTSB (0.59) | CAPN1PPARGCTSBLTA4H | |
| SCHEMBL17865652 | 0.85 | CAPN1 (0.61) | CAPN1CTSB | |
| SCHEMBL3292711 | 0.85 | CAPN1 (0.61) | CAPN1CTSB | |
| SCHEMBL2369340 | 0.85 | CAPN1 (0.61) | CAPN1CTSB | |
| SCHEMBL2293365 | 0.85 | CAPN1 (0.53) | CAPN1PPARGPPARACTSBFFAR1 | |
| SCHEMBL272162 | 0.84 | BCL2 (0.56) | CAPN1PPARGPPARACTSBLTA4H | |
| SCHEMBL4460974 | 0.84 | BCL2 (0.56) | CAPN1PPARGPPARACTSBLTA4H | |
| SCHEMBL5353421 | 0.84 | BCL2 (0.56) | CAPN1PPARGPPARACTSBLTA4H | |
| SCHEMBL9069670 | 0.82 | CTSK (0.61) | CAPN1PPARGCTSBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135424-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-11-25 | — | — | WO | disclosed |