Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.53 |
| ▸ | ACACA | Q13085 | 4/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727055 | 0.90 | ACACB (0.56) | ACACBACACAMTNR1AMTNR1BSCN9A | |
| SCHEMBL3717125 | 0.85 | MTNR1A (0.64) | ACACBMTNR1AMTNR1BSCN9A | |
| SCHEMBL3726989 | 0.85 | MTNR1A (0.50) | ACACBACACAMTNR1AMTNR1BSCN9A | |
| SCHEMBL3724129 | 0.85 | MTNR1A (0.53) | ACACBACACAMTNR1AMTNR1BSCN9A | |
| SCHEMBL3728649 | 0.85 | MTNR1A (0.55) | ACACBMTNR1AMTNR1B | |
| SCHEMBL3721156 | 0.83 | MTNR1A (0.55) | ACACBMTNR1AMTNR1BSCN9A | |
| SCHEMBL3720615 | 0.83 | MTNR1A (0.53) | ACACBACACAMTNR1AMTNR1BSCN9A | |
| SCHEMBL3727352 | 0.83 | MTNR1A (0.50) | ACACBACACAMTNR1AMTNR1BSCN9A | |
| SCHEMBL3722768 | 0.83 | MTNR1A (0.50) | ACACBACACAMTNR1AMTNR1BSCN9A | |
| SCHEMBL3723798 | 0.82 | MTNR1A (0.48) | ACACBACACAMTNR1AMTNR1BSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |