Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724129 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BACACBPKMSMN1; SMN2 | |
| SCHEMBL3726989 | 0.89 | MTNR1A (0.50) | MTNR1AMTNR1BACACBSMN1; SMN2 | |
| SCHEMBL3727055 | 0.88 | ACACB (0.56) | MTNR1AMTNR1BACACBSMN1; SMN2KDM4E | |
| SCHEMBL3720615 | 0.87 | MTNR1A (0.53) | MTNR1AMTNR1BACACBPKMSMN1; SMN2 | |
| SCHEMBL3723798 | 0.86 | MTNR1A (0.48) | MTNR1AMTNR1BACACBSMN1; SMN2 | |
| SCHEMBL3727352 | 0.85 | MTNR1A (0.50) | MTNR1AMTNR1BACACBSMN1; SMN2KDM4E | |
| SCHEMBL3719633 | 0.85 | ACACB (0.53) | MTNR1AMTNR1BACACB | |
| SCHEMBL3720128 | 0.84 | KDM4E (0.45) | PKMSMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL3720513 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BACACBSMN1; SMN2 | |
| SCHEMBL3717771 | 0.82 | MEN1 (0.37) | ACACBSMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |