Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724129 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1BACACBSCN9ASMN1; SMN2 | |
| SCHEMBL3728649 | 0.86 | MTNR1A (0.55) | MTNR1AMTNR1BACACBSMN1; SMN2 | |
| SCHEMBL3726989 | 0.86 | MTNR1A (0.50) | MTNR1AMTNR1BACACBSCN9ASMN1; SMN2 | |
| SCHEMBL3727055 | 0.86 | ACACB (0.56) | MTNR1AMTNR1BACACBSCN9ASMN1; SMN2 | |
| SCHEMBL3719380 | 0.85 | RXRA (0.37) | SCN9ARXRARXRBRXRG | |
| SCHEMBL3720016 | 0.83 | RXRA (0.39) | SCN9ASCN10ARXRARXRBRXRG | |
| SCHEMBL3727352 | 0.83 | MTNR1A (0.50) | MTNR1AMTNR1BACACBSCN9ASMN1; SMN2 | |
| SCHEMBL3720615 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BACACBSCN9ASMN1; SMN2 | |
| SCHEMBL3719633 | 0.82 | ACACB (0.53) | MTNR1AMTNR1BACACBSCN9AACACA | |
| SCHEMBL3720513 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BACACBSCN9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |