Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | YES1 | P07947 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724233 | 0.90 | ACACB (0.37) | MCHR1ALOX5PTGESPPARGPPARD | |
| SCHEMBL3720757 | 0.87 | PPARG (0.38) | MAPTTDP1PPARG | |
| SCHEMBL3717292 | 0.86 | MCHR1 (0.36) | MCHR1ALOX5PTGESMAPTHPGD | |
| SCHEMBL3721927 | 0.86 | PARP10 (0.37) | MCHR1HPGDPPARGPPARD | |
| SCHEMBL3726793 | 0.85 | ADRB2 (0.40) | MAPTTDP1 | |
| SCHEMBL3724672 | 0.84 | MAPT (0.39) | MAPTTDP1 | |
| SCHEMBL3720794 | 0.83 | MTNR1A (0.46) | MCHR1 | |
| SCHEMBL3726373 | 0.82 | ACACB (0.35) | PPARDPPARAPDGFRB | |
| SCHEMBL3724297 | 0.82 | ACACB (0.38) | MCHR1MAPTTDP1HPGDPPARG | |
| SCHEMBL3724495 | 0.80 | PDE3B (0.34) | PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |