Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430834 | 0.77 | POLB (0.57) | POLBROCK2NPC1RAB9AMGLL | |
| SCHEMBL5789238 | 0.75 | NPC1 (0.55) | POLBROCK2NPC1RAB9AMGLL | |
| SCHEMBL2035775 | 0.75 | NPC1 (0.54) | POLBNPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL6965453 | 0.74 | MEN1 (0.46) | POLBNPC1RAB9ASMN1; SMN2LMNA | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.73 | POLB (0.78) | POLBROCK2NPC1RAB9AMGLL | |
| SCHEMBL27924561 | 0.72 | MGLL (0.52) | POLBNPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL2295789 | 0.72 | CA12 (0.66) | POLBNPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL7360148 | 0.71 | MGLL (0.51) | POLBNPC1RAB9AMGLLSMN1; SMN2 | |
| SCHEMBL18640773 | 0.71 | POLB (0.65) | POLBROCK2NPC1RAB9AMGLL | |
| SCHEMBL29777624 | 0.71 | POLB (0.56) | POLBROCK2NPC1RAB9AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127381-A1 | DIAGNOSIS, MONITORING, PROGNOSIS, PREVENTION AND TREATMENT OF ANEURYSMS | JAMES COOK UNIVERSITY (AU) | 2010-11-11 | — | — | WO | disclosed |