Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720573 | 0.91 | LIMK1 (0.33) | MAPTRAB9AL3MBTL1MAPK10MAPK8 | |
| SCHEMBL3719051 | 0.87 | MAPT (0.37) | MAPTRAB9AL3MBTL1ARMAPK10 | |
| SCHEMBL3727500 | 0.85 | MAPK10 (0.40) | MAPTMAPK10MAPK8GAAEPHX2 | |
| SCHEMBL755015 | 0.81 | MAPT (0.43) | MAPTRAB9AL3MBTL1ARGAA | |
| SCHEMBL2545560 | 0.81 | MAPT (0.43) | MAPTRAB9AL3MBTL1ARGAA | |
| SCHEMBL3719026 | 0.77 | MAPT (0.40) | MAPTMAPK10MAPK8GAAEPHX2 | |
| SCHEMBL3730195 | 0.75 | AR (0.48) | AR | |
| SCHEMBL3726016 | 0.74 | L3MBTL1 (0.40) | MAPTRAB9AL3MBTL1ARMAPK10 | |
| SCHEMBL3722579 | 0.74 | L3MBTL1 (0.40) | MAPTRAB9AL3MBTL1ARMAPK10 | |
| SCHEMBL3718921 | 0.74 | L3MBTL1 (0.40) | MAPTRAB9AL3MBTL1ARMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |