Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719954 | 0.91 | MAPT (0.36) | LIMK1MAPK10MAPK8L3MBTL1RAB9A | |
| SCHEMBL3722579 | 0.87 | L3MBTL1 (0.40) | LIMK1MAPK10MAPK8L3MBTL1RAB9A | |
| SCHEMBL3718921 | 0.87 | L3MBTL1 (0.40) | LIMK1MAPK10MAPK8L3MBTL1RAB9A | |
| SCHEMBL3719051 | 0.79 | MAPT (0.37) | MAPK10MAPK8L3MBTL1RAB9AGAA | |
| SCHEMBL3727500 | 0.78 | MAPK10 (0.40) | LIMK1MAPK10MAPK8GAATRPC6 | |
| SCHEMBL3722058 | 0.76 | L3MBTL1 (0.40) | LIMK1MAPK10MAPK8L3MBTL1RAB9A | |
| SCHEMBL2545560 | 0.74 | MAPT (0.43) | L3MBTL1RAB9AGAAMAPTMAPK1 | |
| SCHEMBL755015 | 0.74 | MAPT (0.43) | L3MBTL1RAB9AGAAMAPTMAPK1 | |
| SCHEMBL3725866 | 0.72 | P2RX3 (0.40) | CYP2D6ADRA2AADRA1AP2RX3P2RX2 | |
| SCHEMBL3726016 | 0.72 | L3MBTL1 (0.40) | MAPK10MAPK8L3MBTL1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |