SCHEMBL372

SCHEMBL372

Cc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.60
GAA P10253 2/20 0.60
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
MYC P01106 1/20 0.56
AKR1C3 P42330 1/20 0.56
LTB4R2 Q9NPC1 5/20 0.54
BRS3 P32247 1/20 0.54
HNF4A P41235 1/20 0.53
BCAT2 O15382 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 1/20 0.52
MCL1 Q07820 2/20 0.50
ALDH1A1 P00352 1/20 0.50
ALOX15 P16050 1/20 0.50
UHRF1 Q96T88 1/20 0.49
FABP3 P05413 1/20 0.49
FABP4 P15090 1/20 0.49
FABP5 Q01469 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31402608 1.00 KMT2A (0.60) KMT2AGAANPC1RAB9AMYC
Hydrochloric Acid SCHEMBL7610390 0.98 KMT2A (0.59) KMT2AGAANPC1RAB9AMYC
SCHEMBL18759613 0.89 HNF4A (0.63) KMT2ANPC1RAB9AMYCLTB4R2
SCHEMBL30292805 0.89 HNF4A (0.63) KMT2ANPC1RAB9AMYCLTB4R2
SCHEMBL28897597 0.89 AKR1C3 (0.64) KMT2AGAANPC1RAB9AMYC
SCHEMBL10533851 0.88 SLC6A3 (0.65) KMT2AGAANPC1RAB9AMYC
SCHEMBL11554621 0.87 HNF4A (0.61) KMT2ANPC1RAB9AMYCLTB4R2
SCHEMBL16882044 0.86 KMT2A (0.48) KMT2AGAANPC1RAB9AAKR1C3
Phthalic Acid SCHEMBL28383282 0.85 AKR1C3 (0.54) KMT2AGAANPC1RAB9AMYC
SCHEMBL505412 0.85 HNF4A (0.64) KMT2ANPC1RAB9AMYCLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436833-B Preparation method of telmisartan key intermediate 4' -bromomethyl biphenyl-2-carboxylate 南京红太阳医药研究院有限公司 2024-12-24 CN claimed
CN-119039586-A Modified aromatic polyoxadiazole film and preparation method and application thereof 烟台泰和新材高分子新材料研究院有限公司 2024-11-29 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-115108906-A Novel method for preparing 4 '-bromomethyl- [1,1' -biphenyl ] -2-tert-butyl formate 临海市华南化工有限公司 2022-09-27 CN claimed
US-20220280494-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2022-09-08 US claimed
EP-4021406-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS Delpor, Inc. (US) 2022-07-06 EP claimed
CN-114641291-A Compositions of small molecule therapeutic compounds 戴尔普尔有限公司 2022-06-17 CN claimed
CN-114436833-A Preparation method of telmisartan key intermediate 4' -methylbiphenyl-2-carboxylic ester 南京红太阳医药研究院有限公司 2022-05-06 CN claimed
WO-2021041730-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. (US) 2021-03-04 WO claimed
US-20210000740-A1 COMPOSITIONS FOR SMALL MOLECULE THERAPEUTIC AGENT COMPOUNDS DELPOR, INC. 2021-01-07 US claimed
US-7736630-B2 Products for preventing penetration into the skin YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2010-06-15 US claimed
EP-1169289-B1 METHOD FOR PRODUCING DERIVATIVES OF BIPHENYL-2-CARBOXYLIC ACID BOEHRINGER INGELHEIM PHARMA (DE) 2003-10-29 EP claimed
EP-0978503-B1 Synthesis of t-butyl o-(p-tolyl)benzoate by reaction of o-(p-tolyl)benzoic acid with isobutene using acid catalysis CLARIANT GMBH (DE) 2003-05-07 EP claimed
US-6369266-B1 Process for producing tert-butyl 4′-methyl-2-biphenylcarboxlate SUMIKA FINE CHEMICALS, CO.,LTD. (JP) 2002-04-09 US claimed
US-6369271-B1 SAPONIFICATION WITH HYDROCHLORIC ACID, HEATING WITH PRESSURIZATION BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-04-09 US claimed
EP-1169289-A1 METHOD FOR PRODUCING DERIVATIVES OF BIPHENYL-2-CARBOXYLIC ACID Boehringer Ingelheim Pharma KG (DE) 2002-01-09 EP claimed
EP-1044958-A1 PROCESS FOR PRODUCING tert-BUTYL 4'-METHYL-2-BIPHENYLCARBOXYLATE SUMIKA FINE CHEMICALS Co., Ltd. (JP) 2000-10-18 EP claimed
WO-2000051961-A1 METHOD FOR PRODUCING DERIVATIVES OF BIPHENYL-2-CARBOXYLIC ACID BOEHRINGER INGELHEIM PHARMA KG (DE) 2000-09-08 WO claimed
EP-0978503-A1 Synthesis of t-butyl o-(p-tolyl)benzoate by reaction of o-(p-tolyl)benzoic acid with isobutene using acid catalysis Clariant GmbH (DE) 2000-02-09 EP claimed
US-5466858-A Ruthenium catalyst, high selectivity with a carboxylic acid UBE INDUSTRIES, LTD. (JP) 1995-11-14 US claimed