Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 3/20 | 0.64 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.63 |
| ▸ | CDC25B | P30305 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | FABP3 | P05413 | 1/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677772 | 1.00 | HNF4A (0.64) | HNF4ABCAT2CDC25BATMFABP3 | |
| SCHEMBL32677769 | 1.00 | HNF4A (0.64) | HNF4ABCAT2CDC25BATMFABP3 | |
| SCHEMBL11554621 | 0.98 | HNF4A (0.61) | HNF4ABCAT2CDC25BATMFABP3 | |
| Biphenyl SCHEMBL9292498 | 0.98 | HNF4A (0.67) | HNF4ABCAT2CDC25BATMFABP3 | |
| Benzene SCHEMBL28480917 | 0.95 | HNF4A (0.69) | HNF4ABCAT2CDC25BATMFABP3 | |
| Benzene SCHEMBL1403559 | 0.95 | HNF4A (0.69) | HNF4ABCAT2CDC25BATMFABP3 | |
| SCHEMBL30292805 | 0.95 | HNF4A (0.63) | HNF4ABCAT2CDC25BATMFABP3 | |
| SCHEMBL18759613 | 0.95 | HNF4A (0.63) | HNF4ABCAT2CDC25BATMFABP3 | |
| SCHEMBL133057 | 0.95 | HNF4A (0.69) | HNF4ABCAT2CDC25BATMFABP3 | |
| SCHEMBL26624744 | 0.95 | HNF4A (0.69) | HNF4ABCAT2CDC25BATMFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738684-B2 | N-terminally modified linear and branched polyamine conjugated peptidomimetics as antimicrobials agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-08-22 | — | — | US | claimed |
| US-20160376306-A1 | N-Terminally Modified Linear and Branched Polyamine Conjugated Peptidomimetics as Antimicrobials Agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-12-29 | — | — | US | claimed |
| EP-0059983-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR USE AS A MEDICAMENT | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-11 | — | — | EP | claimed |
| EP-0059983-A1 | Substituted biphenyl compounds for use as a medicament | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-15 | — | — | EP | claimed |
| CN-110140245-B | Nonaqueous electrolyte secondary battery and material used therein | 三井化学株式会社 | 2022-10-25 | — | — | CN | disclosed |
| CN-110862368-B | Photocatalytic oxidation synthesis method of benzocoumarin compound | 浙江工业大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-110862368-A | Photocatalytic oxidation synthesis method of benzocoumarin compound | 浙江工业大学 | 2020-03-06 | — | — | CN | disclosed |
| EP-2444120-B1 | Spirocyclic amiloride analogues as ENac blockers | NOVARTIS AG (CH) | 2017-09-27 | — | — | EP | disclosed |
| US-9738684-B2 | N-terminally modified linear and branched polyamine conjugated peptidomimetics as antimicrobials agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-08-22 | — | — | US | disclosed |
| US-9643983-B2 | Treating diseases mediated by blockade of the epithelial sodium channel with pyrazine-2-carboxamide derivatives | NOVARTIS AG (CH) | 2017-05-09 | — | — | US | disclosed |
| US-20160376306-A1 | N-Terminally Modified Linear and Branched Polyamine Conjugated Peptidomimetics as Antimicrobials Agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-12-29 | — | — | US | disclosed |
| EP-2231280-B1 | Amiloride-like Pyrazine-carboxamides as ENaC blockers | NOVARTIS AG (CH) | 2016-08-10 | — | — | EP | disclosed |
| WO-1999045925-A1 | NOVEL OPIATE COMPOUNDS, METHODS OF MAKING AND METHODS OF USE | RESEARCH TRIANGLE INSTITUTE (US) | 1999-09-16 | — | — | WO | disclosed |
| EP-0891333-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036875-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| US-4777300-A | Aromatic ketone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-11 | — | — | US | disclosed |
| EP-0232992-A1 | Aromatic ketone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-08-19 | — | — | EP | disclosed |
| EP-0059983-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR USE AS A MEDICAMENT | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |
| US-4578522-A | CHEMICAL INTERMEDIATES FOR BLOOD LIPID CONTROLLING COMPOUNDS | BURROUGHS WELLCOME CO. | 1986-03-25 | — | — | US | disclosed |
| EP-0059983-A1 | Substituted biphenyl compounds for use as a medicament | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376306-A1 | N-Terminally Modified Linear and Branched Polyamine Conjugated Peptidomimetics as Antimicrobials Agents | SRM, CD14, SMS | HNF4A 4634/4885BCAT2 936/4885CDC25B 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.