Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717456 | 0.90 | MTNR1A (0.50) | MTNR1AMTNR1BLMNAMAPTKDM4E | |
| SCHEMBL3724459 | 0.88 | MTNR1A (0.48) | MTNR1AMTNR1BACACBLMNAMAPT | |
| SCHEMBL3726989 | 0.86 | MTNR1A (0.50) | MTNR1AMTNR1BACACB | |
| SCHEMBL3720771 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BACACBLMNAMAPT | |
| SCHEMBL3720478 | 0.84 | GLA (0.40) | ACACBLMNAKDM4E | |
| SCHEMBL3720064 | 0.84 | ACACB (0.50) | MTNR1AMTNR1BACACB | |
| SCHEMBL3719892 | 0.82 | ACACB (0.32) | ACACBLMNAMAPTHIF1ARXFP1 | |
| SCHEMBL3720627 | 0.82 | MTNR1A (0.50) | MTNR1AMTNR1BACACBLMNAMAPT | |
| SCHEMBL3723076 | 0.82 | MTNR1A (0.50) | MTNR1AMTNR1BACACBMAPTALDH1A1 | |
| SCHEMBL3720513 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BACACBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |