Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718483 | 0.89 | MAPT (0.38) | CRHR1MAPTP2RX3PGK1ALDH1A1 | |
| SCHEMBL3720739 | 0.88 | MAPT (0.39) | CRHR1MAPTP2RX3ALDH1A1GAA | |
| SCHEMBL3719833 | 0.87 | P2RX3 (0.39) | CRHR1MAPTP2RX3ALDH1A1GAA | |
| SCHEMBL3720773 | 0.87 | P2RX3 (0.41) | MAPTP2RX3PGK1GAAHPGD | |
| SCHEMBL3726852 | 0.85 | P2RX3 (0.43) | MAPTP2RX3ALDH1A1GAAPDE3B | |
| SCHEMBL3719378 | 0.85 | MAPT (0.39) | MAPTP2RX3KDM4EGAAHPGD | |
| SCHEMBL3718569 | 0.84 | MAPT (0.37) | MAPTP2RX3PGK1 | |
| SCHEMBL3717014 | 0.82 | MAPT (0.34) | MAPTP2RX3ALDH1A1GAAMAPK1 | |
| SCHEMBL3720742 | 0.82 | MAPT (0.37) | MAPTP2RX3TP53 | |
| SCHEMBL3719557 | 0.81 | MAPT (0.42) | MAPTP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |