Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718483 | 0.93 | MAPT (0.38) | MAPTP2RX3BLML3MBTL1MEN1 | |
| SCHEMBL3720742 | 0.89 | MAPT (0.37) | MAPTP2RX3BLML3MBTL1SCN7A | |
| SCHEMBL3719433 | 0.89 | MAPT (0.39) | MAPTBLML3MBTL1SCN7AKCNH2 | |
| SCHEMBL3719949 | 0.88 | RORC (0.39) | MAPTP2RX3L3MBTL1KCNH2HTT | |
| SCHEMBL3726082 | 0.88 | MAPT (0.37) | MAPTBLML3MBTL1SCN7AKCNH2 | |
| SCHEMBL3721856 | 0.87 | MAPT (0.37) | MAPTBLML3MBTL1SCN7AKCNH2 | |
| SCHEMBL3726852 | 0.86 | P2RX3 (0.43) | MAPTP2RX3BLML3MBTL1KMT2A | |
| SCHEMBL3717622 | 0.85 | MAPT (0.32) | MAPTP2RX3TLR8 | |
| SCHEMBL3720126 | 0.84 | CRHR1 (0.39) | MAPTP2RX3PGK1 | |
| SCHEMBL3717500 | 0.83 | MAPT (0.39) | MAPTBLMMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |