Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720739 | 0.85 | MAPT (0.39) | MAPTP2RX3NPC1RAB9AGAA | |
| SCHEMBL3720742 | 0.85 | MAPT (0.37) | MAPTTLR8P2RX3ATML3MBTL1 | |
| SCHEMBL3727136 | 0.84 | MAPT (0.34) | MAPTELANE | |
| SCHEMBL3717622 | 0.84 | MAPT (0.32) | MAPTTLR8P2RX3NPC1RAB9A | |
| SCHEMBL3718569 | 0.83 | MAPT (0.37) | MAPTTLR8P2RX3HTTATM | |
| SCHEMBL3720773 | 0.82 | P2RX3 (0.41) | MAPTP2RX3GAAHPGDHTT | |
| SCHEMBL3718483 | 0.82 | MAPT (0.38) | MAPTP2RX3HTTATML3MBTL1 | |
| SCHEMBL3720126 | 0.82 | CRHR1 (0.39) | MAPTP2RX3NPC1RAB9AGAA | |
| SCHEMBL3719833 | 0.82 | P2RX3 (0.39) | MAPTP2RX3NPC1RAB9AELANE | |
| SCHEMBL3719949 | 0.82 | RORC (0.39) | MAPTP2RX3GAAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |