Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727694 | 0.88 | MAPT (0.32) | MAPTLMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3720475 | 0.88 | HTT (0.37) | MAPTLMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3726861 | 0.88 | MAPT (0.32) | MAPTLMNA | |
| SCHEMBL3716747 | 0.84 | MAPT (0.39) | MAPTLMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3727136 | 0.83 | MAPT (0.34) | MAPTELANE | |
| SCHEMBL3720739 | 0.82 | MAPT (0.39) | MAPT | |
| SCHEMBL3720648 | 0.81 | MAPT (0.36) | MAPT | |
| SCHEMBL3720723 | 0.80 | MAPT (0.44) | MAPTELANE | |
| SCHEMBL3720189 | 0.79 | TSHR (0.34) | LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL3720275 | 0.79 | LMNA (0.32) | LMNACYP1A2CYP2C19SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |