Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720187 | 0.88 | MAPT (0.32) | MAPTLMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3727694 | 0.88 | MAPT (0.32) | MAPTLMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3719337 | 0.86 | HPGD (0.38) | HTTHPGDGAAATML3MBTL1 | |
| SCHEMBL3716747 | 0.84 | MAPT (0.39) | ATML3MBTL1MAPTLMNACYP1A2 | |
| SCHEMBL3720773 | 0.82 | P2RX3 (0.41) | HTTHPGDGAAATML3MBTL1 | |
| SCHEMBL3725385 | 0.80 | MAPT (0.43) | HTTHPGDGAAATML3MBTL1 | |
| SCHEMBL3727136 | 0.80 | MAPT (0.34) | MAPT | |
| SCHEMBL3720104 | 0.80 | ACACB (0.43) | HTTHPGDGAAATML3MBTL1 | |
| SCHEMBL3720478 | 0.79 | GLA (0.40) | ATMACACBLMNACYP1A2SMN1; SMN2 | |
| SCHEMBL3719892 | 0.79 | ACACB (0.32) | HTTMAPTACACBLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |