Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726843 | 0.83 | LTA4H (0.49) | POLBMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL5907200 | 0.77 | NQO1 (0.64) | POLBMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL22874671 | 0.75 | MAOB (0.57) | POLBMAPTNPC1RAB9AAPP | |
| SCHEMBL31499976 | 0.75 | TDP1 (0.44) | MAPTNPC1RAB9AKDM4ETP53 | |
| SCHEMBL3720198 | 0.75 | MAOB (0.54) | ALOX5 | |
| SCHEMBL3722774 | 0.75 | RAB9A (0.49) | POLBMAPTALDH1A1NPC1LMNA | |
| SCHEMBL6376293 | 0.74 | AR (0.62) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL3716712 | 0.74 | CYP1A2 (0.50) | POLBMAPTALDH1A1NPC1LMNA | |
| Hydrochloric Acid SCHEMBL28494253 | 0.73 | AR (0.60) | MAPTALDH1A1NPC1LMNARAB9A | |
| SCHEMBL29629327 | 0.73 | NQO1 (0.68) | MAPTALDH1A1NPC1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |