Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594477 | 0.92 | AKR1C3 (0.46) | RAB9AMAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2559226 | 0.80 | NQO1 (0.61) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL3720198 | 0.79 | MAOB (0.54) | ALOX5MAOB | |
| SCHEMBL3726994 | 0.78 | ACACB (0.42) | MAPTALDH1A1SMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL3722771 | 0.77 | MAOB (0.60) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL3720728 | 0.75 | PTGS1 (0.59) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL9193206 | 0.75 | RAB9A (0.76) | RAB9ANPC1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3720195 | 0.75 | POLB (0.47) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL10017495 | 0.75 | CYP1A2 (0.57) | NPC1LMNASMN1; SMN2TDP1TP53 | |
| SCHEMBL29629327 | 0.74 | NQO1 (0.68) | NPC1MAPTALDH1A1TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |