Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.38 |
| ▸ | GALR2 | O43603 | 3/20 | 0.36 |
| ▸ | GALR1 | P47211 | 3/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722382 | 0.84 | ALOX5 (0.35) | ALOX5KDM4EALDH1A1MAPTBLM | |
| SCHEMBL3720554 | 0.84 | ACACB (0.44) | ALOX5SCN9A | |
| SCHEMBL3728069 | 0.81 | ALOX5 (0.39) | ALOX5SCN9ASCN10A | |
| SCHEMBL3722417 | 0.80 | MEN1 (0.38) | KDM4EMEN1APAF1ALDH1A1MAPT | |
| SCHEMBL3719854 | 0.80 | FGFR2 (0.37) | ALOX5KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3720364 | 0.79 | NCF1 (0.38) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3722547 | 0.78 | PDE4B (0.52) | ALOX5MEN1MAPTKMT2ASCN9A | |
| SCHEMBL3720268 | 0.78 | KDM4E (0.36) | ALOX5KDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL3722574 | 0.78 | SCN9A (0.36) | MAPTSCN9ASCN10A | |
| SCHEMBL3717678 | 0.78 | HTT (0.50) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |