Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 16/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720364 | 0.83 | NCF1 (0.38) | — | |
| SCHEMBL3722359 | 0.82 | ALOX5 (0.42) | ALOX5SCN9ASCN10APDE4B | |
| SCHEMBL3728075 | 0.81 | SCN9A (0.35) | ALOX5SCN9ASCN10A | |
| SCHEMBL3720264 | 0.81 | ALOX5 (0.40) | ALOX5SCN9ASCN10A | |
| SCHEMBL3717959 | 0.80 | MAP4K4 (0.32) | ALOX5SCN9ASCN10APDE4B | |
| SCHEMBL3804254 | 0.79 | TLR8 (0.39) | SCN9ASCN10AKDM4C | |
| SCHEMBL3720041 | 0.79 | MAP4K4 (0.48) | SCN9A | |
| SCHEMBL3722382 | 0.79 | ALOX5 (0.35) | ALOX5SCN9ASCN10APDE4B | |
| SCHEMBL3726203 | 0.78 | PDE4B (0.41) | ALOX5PDE4B | |
| SCHEMBL3720908 | 0.78 | ACACB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |