Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | BLM | P54132 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | F2 | P00734 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | CASP6 | P55212 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838896 | 0.91 | MAPT (0.84) | MEN1KMT2AMAPTBLMGAA | |
| SCHEMBL8082984 | 0.89 | MAPT (0.82) | MEN1KMT2AMAPTBLMGAA | |
| SCHEMBL4667164 | 0.86 | MAPT (1.00) | MEN1KMT2AMAPTBLMGAA | |
| Hydrochloric Acid SCHEMBL5107977 | 0.85 | F2 (0.71) | MEN1KMT2AMAPTBLMGAA | |
| SCHEMBL12310114 | 0.84 | MAPT (0.66) | MEN1KMT2AMAPTBLMGAA | |
| SCHEMBL1465278 | 0.84 | KMT2A (0.70) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL15458727 | 0.84 | MAPT (0.73) | MEN1KMT2AMAPTBLMGAA | |
| SCHEMBL4241915 | 0.83 | HTT (0.64) | MAPTGAAALDH1A1L3MBTL1LMNA | |
| SCHEMBL4337813 | 0.83 | MEN1 (0.68) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL6806474 | 0.82 | MAPT (0.72) | MEN1KMT2AMAPTBLMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418783-B | Preparation method of ezetimibe SSS isomer | 江苏豪森药业集团有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-105439929-A | Synthesis process of ezetimibe intermediate | SHANGHAI HENGSHENG PHARMACEUTICAL CO LTD | 2016-03-30 | — | — | CN | disclosed |
| CN-102358723-A | Preparation method of N-(4-fluorophenyl)-4-benzyloxy benzylidene amine | UNIV ZHEJIANG | 2012-02-22 | — | — | CN | disclosed |
| CN-102358723-A | Preparation method of N-(4-fluorophenyl)-4-benzyloxy benzylidene amine | UNIV ZHEJIANG | 2012-02-22 | — | — | CN | disclosed |
| WO-2010097350-A1 | A PROCESS FOR THE PREPARATION OF AN ALDEHYDE BETA-LACTAM COMPOUND | ADAMED SP. Z O.O. (PL) | 2010-09-02 | — | — | WO | disclosed |