Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 2/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838896 | 0.88 | MAPT (0.84) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL8082984 | 0.86 | MAPT (0.82) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL510619 | 0.86 | HTT (0.58) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL403151 | 0.84 | MAOB (1.00) | MAPTGAAMAOBARBCHE | |
| SCHEMBL4667164 | 0.84 | MAPT (1.00) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL1680561 | 0.83 | LOXL2 (0.57) | MEN1KMT2AMAOBCACNA1BGHSR | |
| SCHEMBL3720530 | 0.82 | MEN1 (0.76) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL7311874 | 0.82 | MAOB (0.86) | MAPTGAAMAOBARBCHE | |
| SCHEMBL15458727 | 0.81 | MAPT (0.73) | MAPTMEN1GAABLMKMT2A | |
| SCHEMBL8618909 | 0.81 | MAOB (0.85) | GAAMAOBARBCHEGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |