Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | THRB | P10828 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | F2 | P00734 | 1/20 | 0.71 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838896 | 0.92 | MAPT (0.84) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL8082984 | 0.90 | MAPT (0.82) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL3720530 | 0.86 | MEN1 (0.76) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL11253865 | 0.85 | MAPT (0.74) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL22776468 | 0.85 | GAA (0.74) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL15458727 | 0.85 | MAPT (0.73) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL158251 | 0.85 | MAPT (0.72) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL6806474 | 0.84 | MAPT (0.72) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL28070143 | 0.83 | MAPT (0.71) | MAPTGAAMEN1BLMKMT2A | |
| SCHEMBL17602106 | 0.83 | MAPT (0.71) | MAPTGAAMEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |