Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667271 | 0.77 | ICMT (0.42) | ARICMT | |
| SCHEMBL3232088 | 0.76 | AR (0.38) | AR | |
| SCHEMBL3764840 | 0.75 | ICMT (0.47) | ARICMT | |
| SCHEMBL16917862 | 0.75 | ICMT (0.38) | ICMT | |
| SCHEMBL13837715 | 0.74 | ICMT (0.36) | ICMT | |
| SCHEMBL7273946 | 0.73 | IMPDH2 (0.59) | AR | |
| SCHEMBL12479971 | 0.72 | AKR1C3 (0.65) | ICMT | |
| SCHEMBL12670808 | 0.71 | — | — | |
| SCHEMBL13967309 | 0.70 | ICMT (0.37) | ICMT | |
| SCHEMBL5154364 | 0.70 | ICMT (0.44) | ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142516-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | Sanofi-Aventis (FR) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008121670-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI-AVENTIS (FR) | 2008-10-09 | — | — | WO | disclosed |