Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720570 | 0.67 | ACHE (0.33) | KDM4EALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL1615309 | 0.65 | CARM1 (0.39) | KDM4EALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL1282974 | 0.62 | ACHE (0.50) | KDM4EALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL12985890 | 0.60 | — | — | |
| SCHEMBL12471012 | 0.60 | CARM1 (0.39) | ACHEBACE1 | |
| SCHEMBL11934739 | 0.60 | MAPT (0.48) | ALDH1A1MAPTACHEBACE1 | |
| SCHEMBL13438624 | 0.60 | MAPT (0.48) | ALDH1A1MAPTACHEBACE1 | |
| SCHEMBL694781 | 0.58 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL31757640 | 0.58 | POLB (0.52) | KDM4EALDH1A1MAPTACHEBACE1 | |
| SCHEMBL11935195 | 0.57 | GAA (0.58) | KDM4EALDH1A1GAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |