Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728071 | 0.75 | MET (0.33) | ACHEBACE1METSCN9A | |
| SCHEMBL3719936 | 0.75 | MET (0.35) | ACHEBACE1METALOX5EGLN1 | |
| SCHEMBL3317518 | 0.74 | HTT (0.45) | KDM4EALDH1A1MAPK1SCN9A | |
| SCHEMBL4655065 | 0.73 | HTT (0.45) | KDM4EALDH1A1MAPTMAPK1EGLN1 | |
| SCHEMBL13583086 | 0.70 | MEN1 (0.34) | ALDH1A1GAAMAPTALOX5 | |
| SCHEMBL13076464 | 0.70 | ACACA (0.48) | — | |
| SCHEMBL3717406 | 0.70 | ACACB (0.35) | — | |
| SCHEMBL1615309 | 0.68 | CARM1 (0.39) | ACHEBACE1KDM4EALDH1A1GAA | |
| SCHEMBL3720567 | 0.67 | KDM4E (0.34) | ACHEBACE1KDM4EALDH1A1GAA | |
| SCHEMBL3720087 | 0.65 | MAPT (0.38) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |