Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808580 | 0.81 | IDO1 (0.47) | ALOX15IDO1TDP1ALOX12ALDH1A1 | |
| SCHEMBL3724489 | 0.78 | TDP1 (0.46) | ALOX15IDO1TDP1ALOX12ALDH1A1 | |
| SCHEMBL5374248 | 0.78 | TDP1 (0.41) | ALOX15IDO1TDP1ALOX12ALDH1A1 | |
| SCHEMBL13145946 | 0.77 | ALOX15 (0.50) | ALOX15IDO1ALOX12ALDH1A1HSD17B10 | |
| SCHEMBL25069190 | 0.76 | IDO1 (0.43) | ALOX15IDO1TDP1ALOX12ALDH1A1 | |
| SCHEMBL14453838 | 0.76 | IDO1 (0.43) | ALOX15IDO1TDP1ALOX12ALDH1A1 | |
| SCHEMBL26239891 | 0.76 | MEN1 (0.46) | ALOX15IDO1TDP1ALOX12ALDH1A1 | |
| SCHEMBL14453835 | 0.76 | ALDH1A1 (0.47) | ALOX15IDO1TDP1ALOX12ALDH1A1 | |
| SCHEMBL13727629 | 0.76 | ABL1 (0.47) | ALOX15TDP1ALOX12ALDH1A1HSD17B10 | |
| SCHEMBL693623 | 0.74 | PKM (0.54) | TDP1ALDH1A1HSD17B10LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |