Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713318 | 0.91 | KMT2A (0.46) | — | |
| SCHEMBL3712432 | 0.90 | ACACB (0.47) | KDM1AHDAC1ACACBBCHEMAOA | |
| SCHEMBL13187705 | 0.90 | HDAC1 (0.55) | KDM1AHDAC1ACACB | |
| SCHEMBL3712370 | 0.88 | ACP1 (0.47) | — | |
| SCHEMBL13187744 | 0.87 | HDAC1 (0.51) | KDM1AHDAC1 | |
| SCHEMBL3709560 | 0.85 | KMO (0.50) | KMOACACBBCHEMAOAACHE | |
| SCHEMBL3709419 | 0.84 | PARP1 (0.45) | HDAC1HRH3 | |
| SCHEMBL13187707 | 0.82 | HDAC1 (0.48) | KDM1AHDAC1 | |
| SCHEMBL13188620 | 0.82 | KMO (0.47) | KMOACACBBCHEMAOAACHE | |
| SCHEMBL3716614 | 0.80 | HDAC1 (0.49) | KDM1AHDAC1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |