Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | F13A1 | P00488 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720092 | 0.87 | KDM4E (0.50) | KDM4EF13A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3727291 | 0.87 | KDM4E (0.50) | KDM4EF13A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3726453 | 0.85 | KDM4E (0.63) | KDM4EF13A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3726323 | 0.83 | SMN1; SMN2 (0.43) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL3720173 | 0.82 | KDM4E (0.70) | KDM4EF13A1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3723843 | 0.80 | PARP15 (0.41) | SMN1; SMN2MTNR1AMTNR1BACACB | |
| SCHEMBL3719877 | 0.77 | SMN1; SMN2 (0.74) | KDM4ESMN1; SMN2LMNAMAPTMTNR1A | |
| SCHEMBL3722351 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL3726746 | 0.76 | ACACB (0.53) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3719665 | 0.76 | ACACB (0.54) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |