Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718635 | 0.89 | PPARA (0.45) | SMN1; SMN2ALDH1A1RAB9AMTNR1AMTNR1B | |
| SCHEMBL3720850 | 0.84 | PPARA (0.43) | SMN1; SMN2ALDH1A1RAB9AMTNR1AMTNR1B | |
| SCHEMBL3720745 | 0.83 | KDM4E (0.51) | SMN1; SMN2ALDH1A1MTNR1AMTNR1BKDM4E | |
| SCHEMBL3723843 | 0.81 | PARP15 (0.41) | SMN1; SMN2MTNR1AMTNR1BACACB | |
| SCHEMBL3722380 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MTNR1AMTNR1BKDM4E | |
| SCHEMBL3726746 | 0.78 | ACACB (0.53) | SMN1; SMN2ALDH1A1MTNR1AMTNR1BACACB | |
| SCHEMBL3726321 | 0.78 | CYP2C9 (0.52) | ALDH1A1CYP1A2CYP2C9KDM4EACACB | |
| SCHEMBL3719583 | 0.77 | ALDH1A1 (0.42) | ALDH1A1RAB9ACYP1A2CYP2C9KDM4E | |
| SCHEMBL3722465 | 0.76 | TRPV1 (0.43) | SMN1; SMN2ALDH1A1MTNR1AMTNR1BKDM4E | |
| SCHEMBL3720296 | 0.76 | SCN9A (0.45) | SMN1; SMN2ALDH1A1RAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |