Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724568 | 0.89 | ACACB (0.44) | ACACBMTNR1AMTNR1BSCN7AKCNH2 | |
| SCHEMBL3721546 | 0.89 | ACACB (0.45) | ACACBMTNR1AMTNR1BSCN7AKCNH2 | |
| SCHEMBL3717955 | 0.83 | SCN7A (0.49) | ACACBMTNR1AMTNR1BSCN7AKCNH2 | |
| SCHEMBL3724310 | 0.83 | SCN7A (0.49) | ACACBMTNR1AMTNR1BSCN7AKCNH2 | |
| SCHEMBL3726818 | 0.81 | ACACB (0.64) | ACACBMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL3726453 | 0.81 | KDM4E (0.63) | ACACBMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL3727069 | 0.79 | MTNR1A (0.62) | ACACBMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL3719542 | 0.78 | MTNR1A (0.48) | ACACBMTNR1AMTNR1B | |
| SCHEMBL3720307 | 0.78 | MTNR1A (0.61) | ACACBMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL3727134 | 0.78 | ACACB (0.67) | ACACBMTNR1AMTNR1BSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |