Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24708505 | 0.87 | SMN1; SMN2 (0.61) | MTNR1AMTNR1BSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3720307 | 0.87 | MTNR1A (0.61) | MTNR1AMTNR1BSMN1; SMN2ACACB | |
| SCHEMBL3724114 | 0.86 | SMN1; SMN2 (0.62) | MTNR1AMTNR1BSMN1; SMN2KDM4ELMNA | |
| SCHEMBL3719870 | 0.85 | LTA4H (0.53) | MTNR1AMTNR1BSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3726818 | 0.82 | ACACB (0.64) | MTNR1AMTNR1BSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3726453 | 0.82 | KDM4E (0.63) | MTNR1AMTNR1BSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13895358 | 0.81 | KDM4E (0.58) | MTNR1AMTNR1BSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3717478 | 0.79 | ACACB (0.64) | MTNR1AMTNR1BSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3720004 | 0.79 | ACACB (0.64) | MTNR1AMTNR1BSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3719877 | 0.79 | SMN1; SMN2 (0.74) | MTNR1AMTNR1BSMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |