Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10971032 | 0.85 | ALDH1A1 (0.54) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL9587990 | 0.84 | ALDH1A1 (0.56) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL3722747 | 0.84 | HTT (0.47) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL11310987 | 0.83 | MAPT (0.53) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL3724731 | 0.82 | ALDH1A1 (0.47) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL10469281 | 0.81 | ALDH1A1 (0.41) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL10469282 | 0.81 | ALDH1A1 (0.41) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL30946287 | 0.80 | ALDH1A1 (0.60) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL30735548 | 0.80 | ALDH1A1 (0.60) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL27259702 | 0.80 | ALDH1A1 (0.60) | HTTALDH1A1RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |