Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720887 | 0.82 | HTT (0.47) | ALDH1A1LMNACYP1A2HPGDNPSR1 | |
| SCHEMBL3722747 | 0.82 | HTT (0.47) | ALDH1A1LMNACYP1A2HPGDNPSR1 | |
| SCHEMBL3719822 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNACYP1A2HPGDNPSR1 | |
| SCHEMBL30134301 | 0.79 | OGA (0.41) | ALDH1A1LMNACYP1A2HPGDNPSR1 | |
| SCHEMBL3718562 | 0.77 | HTT (0.62) | ALDH1A1LMNACYP1A2HPGDNPSR1 | |
| SCHEMBL3719825 | 0.77 | ALDH1A1 (0.45) | ALDH1A1LMNACYP1A2HPGDNPSR1 | |
| SCHEMBL25804159 | 0.74 | OGA (0.41) | ALDH1A1LMNACYP1A2HPGDNPSR1 | |
| SCHEMBL30133952 | 0.74 | OGA (0.41) | ALDH1A1LMNACYP1A2HPGDNPSR1 | |
| SCHEMBL3717665 | 0.73 | UGT2B7 (0.53) | LMNACYP1A2MAPTKMT2AL3MBTL1 | |
| SCHEMBL24261109 | 0.72 | ALDH1A1 (0.55) | ALDH1A1LMNACYP1A2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |