Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719115 | 0.80 | KDM4E (0.33) | TDP1ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL22345556 | 0.76 | PKM (0.52) | SMN1; SMN2KMT2ATDP1PKMALDH1A1 | |
| SCHEMBL20459309 | 0.75 | SMN1; SMN2 (0.45) | DPP4SMN1; SMN2KMT2ATDP1PKM | |
| SCHEMBL907575 | 0.73 | SMN1; SMN2 (0.43) | DPP4SMN1; SMN2KMT2ATDP1PKM | |
| SCHEMBL3720886 | 0.70 | MEN1 (0.40) | DPP4SMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL30959500 | 0.70 | DPP4 (0.41) | DPP4SMN1; SMN2KMT2ATDP1PKM | |
| SCHEMBL12478230 | 0.69 | SMN1; SMN2 (0.40) | DPP4SMN1; SMN2KMT2ATDP1PKM | |
| SCHEMBL10299384 | 0.69 | SMN1; SMN2 (0.42) | DPP4SMN1; SMN2KMT2ATDP1PKM | |
| SCHEMBL29104397 | 0.68 | CA12 (0.50) | SMN1; SMN2KMT2APKMCA12CA1 | |
| SCHEMBL8863393 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2APKMCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010125469-A1 | PYRIMIDINEDIONE-FUSED HETEROCYCLIC COMPOUNDS AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-11-04 | — | — | WO | disclosed |