Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139377 | 0.92 | SCN9A (0.72) | SCN9A | |
| SCHEMBL24518040 | 0.86 | SCN9A (0.55) | SCN9A | |
| SCHEMBL17350078 | 0.84 | CTSA (0.51) | SCN9A | |
| SCHEMBL3131628 | 0.84 | SCN9A (0.51) | SCN9A | |
| SCHEMBL28876906 | 0.82 | SCN9A (0.62) | SCN9A | |
| SCHEMBL3134594 | 0.81 | SCN10A (0.60) | SCN9A | |
| SCHEMBL16129931 | 0.80 | SCN9A (0.56) | SCN9A | |
| SCHEMBL29911672 | 0.80 | SCN9A (0.57) | SCN9A | |
| SCHEMBL28052676 | 0.80 | SCN9A (0.57) | SCN9A | |
| SCHEMBL16129942 | 0.80 | ALDH1A1 (0.62) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614201-B2 | Heterocyclic amides as modulators of TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-24 | — | — | US | claimed |
| WO-2010141805-A1 | HETEROCYCLIC AMIDES AS MODULATORS OF TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | claimed |
| CN-107108568-A | Pesticidally active amide heterocyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| US-8614201-B2 | Heterocyclic amides as modulators of TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-24 | — | — | US | disclosed |
| WO-2010141805-A1 | HETEROCYCLIC AMIDES AS MODULATORS OF TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | disclosed |