SCHEMBL28876906

SCHEMBL28876906

NC(=O)c1cccc(-c2ccc(F)cc2)n1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 18/20 0.62
HSD17B14 Q9BPX1 1/20 0.56
DGAT1 O75907 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3139184 0.91 SCN9A (0.72) SCN9A
SCHEMBL16129942 0.84 ALDH1A1 (0.62) SCN9ADGAT1
SCHEMBL30367705 0.84 HSD17B14 (0.57) SCN9AHSD17B14
SCHEMBL1137226 0.84 HSD17B14 (0.57) SCN9AHSD17B14
SCHEMBL16129931 0.84 SCN9A (0.56) SCN9ADGAT1
SCHEMBL29648185 0.84 DGAT1 (0.56) SCN9AHSD17B14DGAT1
SCHEMBL608430 0.84 DGAT1 (0.56) SCN9AHSD17B14DGAT1
SCHEMBL18287241 0.83 HSD17B14 (0.56) SCN9AHSD17B14
SCHEMBL13270856 0.83 DGAT1 (0.52) SCN9ADGAT1
SCHEMBL3721065 0.82 SCN9A (0.63) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110195238-A A kind of method that the electrochemistry dechlorination of trichloromethyl pyridine derivative prepares amide 浙江工业大学 2019-09-03 CN disclosed