Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12483808 | 0.77 | KMT2A (0.52) | KDM4EKMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28901141 | 0.76 | KMT2A (0.52) | KDM4EKMT2ASMN1; SMN2RAB9AGAA | |
| SCHEMBL5317075 | 0.76 | KDM4E (0.62) | KDM4EKMT2AHRH3LTA4HPTGS2 | |
| SCHEMBL5687538 | 0.76 | KDM4E (0.50) | KDM4EKMT2AHRH3LTA4HPTGS2 | |
| SCHEMBL5208559 | 0.76 | KMT2A (0.45) | KDM4EKMT2AHRH3LTA4HPTGS2 | |
| SCHEMBL258619 | 0.75 | HSP90AA1 (0.57) | KMT2AALDH1A1KMOTHRATHRB | |
| SCHEMBL11352994 | 0.74 | GAA (0.49) | KDM4EKMT2AHRH3LTA4HPTGS2 | |
| SCHEMBL13505713 | 0.73 | LTA4H (0.46) | KDM4EKMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11411966 | 0.71 | THRB (0.58) | KMT2ARAB9AMAPK1MAPTTHRB | |
| SCHEMBL9445013 | 0.70 | HSP90AA1 (0.68) | KMT2ASLC6A2SLC6A4SLC6A3HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |