Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726761 | 0.84 | SMN1; SMN2 (0.35) | FFAR1RAB9ATDP1L3MBTL1GAA | |
| SCHEMBL30594477 | 0.80 | AKR1C3 (0.46) | RAB9AAKR1C3AKR1C2PTGS1TDP1 | |
| SCHEMBL3722415 | 0.77 | ACACB (0.51) | PTGS1MAPTHTTKDM4ELMNA | |
| SCHEMBL3721719 | 0.77 | PPARA (0.35) | PPARDPPARGPPARATDP1HTT | |
| SCHEMBL3719442 | 0.76 | ACACB (0.40) | MAPK1MAPTLTA4HKDM4E | |
| SCHEMBL3720059 | 0.76 | MAOB (0.43) | RAB9AL3MBTL1GAAMAPK1MAOB | |
| SCHEMBL3724221 | 0.75 | S1PR1 (0.35) | — | |
| SCHEMBL3722774 | 0.73 | RAB9A (0.49) | RAB9AAKR1C3AKR1C2TDP1L3MBTL1 | |
| SCHEMBL3726994 | 0.73 | ACACB (0.42) | FFAR1AKR1C3AKR1C2CYP1A2CA12 | |
| SCHEMBL3719408 | 0.72 | LTA4H (0.47) | FFAR1RAB9AL3MBTL1MAOBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |